Outside of the Es season, 6m appears very quiet. With Es, I find that with a few watts and a simple antenna it is easy to work all over Europe and North Africa on SSB. Last year and the year before my 2W was copied in Israel and I copied Kazakhstan on WSPR.
Since discovering 6m MSK144 I have learnt that DX is possible at almost any time. Most of my MSK144 reception has been aircraft reflection, but some remarkable DX seems to have been by random MS. Judging by the reports, I am sure I could work MS DX by MSK144 in a decent MS shower.